Module 1
Hypertriglyceridemia (HTG): Basic Pathophysiology
In this introductory module, participants will gain a clear understanding of the underlying mechanisms that drive hypertriglyceridemia. Learners will explore:
- How triglycerides are normally synthesized, transported, and metabolized in the body
- The role of lipoproteins, enzymes (e.g., LPL, ApoC-III), and hormonal regulation in triglyceride balance
- Genetic and acquired factors that lead to elevated triglycerides
- The pathophysiologic link between severe HTG and complications such as pancreatitis and increased cardiovascular risk
By the end of this module, participants will be able to explain the key pathways involved in triglyceride metabolism, recognize the mechanisms that contribute to dysregulation, and set the foundation for evaluating and treating patients with elevated triglycerides.